Granisetron Kabi Caution For Usage

Special precautions for disposal: For single use only. Any unused portion should be discarded.
The diluted injections and infusions are to be inspected visually for particulate matter prior to administration. They should only be used if the solution is clear and free from particles.
Preparing the infusion: Adults: The solution should be diluted to 5 ml per mg. i.e the contents of a 1 ml ampoule can be diluted to a volume of 5 ml; the contents of a 3 ml ampoule can be diluted to a volume of 15 ml.
Granisetron can also be diluted in 20 to 50 ml compatible infusion fluid and then given over five minutes as an intravenous infusion in any of the following solutions: 0.9 % w/v sodium chloride injection, 5 % w/v glucose injection, Lactated Ringer's Solution. No other diluents should be used.
Use in the paediatric population: Children 2 years of age and older: To prepare the dose of 10-40 μg/kg, the appropriate volume is withdrawn and diluted with infusion fluid (as for adults) to a total volume of 10 to 30 ml.
As a general precaution, Granisetron should not be mixed in solution with other drugs.
Granisetron 1 mg/ml is compatible with Dexamethasone dihydrogenphosphate dinatrium in a concentration of 10-60 μg/ml of Granisetron and 80-480 μg/ml Dexamethasonphosphate diluted in sodium chloride 0.9 % or Glucose 5 % solution over a period of 24 hours.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Incompatibilities: This medicinal product must not be mixed with other medicinal products except those mentioned previously.